Nerve growth factor protects cholinergic neurons against quinolinic acid-induced excitotoxicity in wistar rats
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منابع مشابه
Udk 619:616.831-003.8 Nerve Growth Factor Protects Cholinergic Neurons against Quinolinic Acid-induced Excitotoxicity in Wistar Rats
The etiology of neuronal death in neurodegenerative diseases, including Huntington's disease (HD) is still unknown. There could be a complex interplay between altered energy metabolism, excitotoxicity and oxidative stress. Excitotoxic striatal lesions induced by quinolinic acid (QA), were used to test for the neuroprotective actions of nerve growth factor (NGF) on striatal cholinergic and GABAe...
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In this study, we demonstrate that cholecystokinin-8 (CCK-8) induces an increase in both nerve growth factor (NGF) protein and NGF mRNA in mouse cortex and hippocampus when i.p. injected at physiological doses. By using fimbria-fornix-lesioned mice, we have also demonstrated that repeated CCK-8 i.p. injections result in recovery of lesion-induced NGF deficit in septum and restore the baseline N...
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ژورنال
عنوان ژورنال: Acta veterinaria
سال: 2004
ISSN: 0567-8315
DOI: 10.2298/avb0403105v